Procede d'elaboration de derives d'acide 4-chloro-3-[5- chloro-1-(2,4-dimethoxybenzyl)-3-alkyl-2-oxo-2,3-dihydro-1h-indol-3-yl]benzoique de type racemique et optiquement actif par catalyseur a transfert de phase

Process for the preparation of racemic and optically active 4-chloro-3-[5-chloro-1-(2,4-dimethoxybenzyl)-3-alkyl-2-oxo-2,3-dihydro-1h-indol-3-yl]benzoic acid derivatives using a phase transfer catalyst

Abstract

Procédé d'élaboration de dérivés d'acide 4-chloro-3-[5-chloro-1-(2,4-diméthoxybenzyl)-3-alkyl-2-oxo-2,3-dihydro-lH-indol-3-yl]benzoïque de type racémique et optiquement actif de formule générale (I), dans laquelle R est un atome d'hydrogène ou un groupe alkyle droit ou ramifié à 1-4 atomes de carbone et R1 un groupe alkyle droit ou ramifié à 1-4 atomes de carbone.
The invention relates to a process for the preparation of racemic and optically active 4-chloro-3-[5-chloro-1-(2,4-dimethoxybenzyl)-3-alkyl-2-oxo-2,3-dihydro-lH-indol-3-yl]benzoic acid derivatives of the general formula (I), wherein R represents a hydrogen atom or a straight or branched alkyl group containing 1-4 carbon atoms and R1 represents a straight or branched alkyl group containing 1-4 carbon atoms.

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